Patients should contact their GP or prescribing clinician if they experience: Severe or persistent heartburn that does not respond to over-the-counter treatments or lifestyle modifications within 23 weeks Difficulty or pain when swallowing (dysphagia or odynophagia), which may indicate oesophageal inflammation or stricture Persistent nausea or vomiting , particularly if unable to keep down fluids or medications Unintended weight loss beyond the expected therapeutic effect, or signs of malnutrition Blood in vomit (haematemesis) or black, tarry stools (melaena), which may indicate gastrointestinal bleeding Severe upper abdominal pain , especially if radiating to the back, which could suggest pancreatitisa rare but serious adverse effect of GLP-1 receptor agonists [1] [2] Right upper quadrant pain, fever, or jaundice , which could indicate gallbladder diseasea known risk with GLP-1 receptor agonists and rapid weight loss [1] [2] Red flag symptoms requiring urgent assessment include chest pain (to exclude cardiac causes), severe persistent vomiting leading to dehydration, or any signs of gastrointestinal bleeding
Dev told us, Were going to help you navigate your insurance and figure out an affordable option, or maybe you should be on this drug instead of that drug
2014;9(1): e87488
Even though GLP-1s have been around for over a decade (they were originally designed to treat type 2 diabetes), theyve only recently hit the mainstream thanks to buzzy celeb shoutouts, TikTok transformation videos, and FDA approvals that basically turned them into household names
